Wright Lab

Illuminating the inner-workings of bacterial and viral pathogens by cryo-electron microscopy

Dr. Jae Yang loading Cryo-samples into the Aquilos cryo-FIB-SEM.

Cryo-CLEM workflow for studies of mitochondria in virus-infected cells.

CbK bacteriophage that infects Caulobacter crescentus.

Visualizing Biology Across Scales.

The Wright Laboratory develops and applies cryo-electron microscopy (cryo-EM), cryo-electron tomography (cryo-ET), cryogenic correlative microscopy, and advanced computational methods to determine the three-dimensional organization of viruses, cells, and tissues. Our work combines technology development with biological discovery to reveal molecular mechanisms underlying infection, cellular organization, and disease.

Located at the University of Wisconsin–Madison, the laboratory also leads the Cryo-EM Research Center (CEMRC) and the NIH-funded Midwest Center for Cryo-Electron Tomography (MCCET), supporting researchers across Wisconsin, the Midwest, and the United States.

UW–Madison Science Events

  • June
    • June 3
      Insects of the Preservewith the Friends of the Lakeshore Nature Preserve6:00 PM, Picnic Point entrance kiosk, University of Wisconsin-Madison, 2000 University Bay Drive, Madison WI 53705
    • June 5
      Lake Wingra Nature Everywhere ChallengeArboretum Community EventAll day
    • June 5
      Ophthalmology Grand Rounds - VirtualAmitha Domalpally, MD, PhD, "Age-related Macular Degeneration: Evolving Classification and Biomarkers;" Gordon Crabtree, MD, "Age-Related Macular Degeneration: Evolving Classification and Biomarkers"7:00 AM, Online

UW-Madison Academic Calendar