Illuminating the inner-workings of bacterial and viral pathogens by cryo-electron microscopy

Jae Yang, Ph.D.

Position title: Scientist I

Email: jyang525@wisc.edu

Jae is an assistant scientist in the Wright lab, the Cryo-EM Research Center, and the Midwest Center for Cryo-Electron Tomography at UW-Madison. Jae completed her Ph.D. under the mentorship of Dr. Esther Bullitt at Boston University. She studied the ultrastructure and complexity of infectious extracellular vesicles released from cells infected by non-enveloped positive-sense RNA viruses using cryo-ET and mass spectrometry. After graduation, Jae joined Dr. Wright’s group at UW-Madison and has focused on development of high-precision cryo-CLEM with flexible workflows and an easy-to-use software toolkit. She also works on cryo-EM sample optimization through micro-patterning and improvement of freezing conditions for cell-virus and cell-bacteria interactions, VLPs for vaccine development, and purified viral glycoproteins.